Curcumin is the main active ingredient in turmeric. Studies suggest that curcumin has incredible benefits against depression. A controlled trial including 60 people with depression has proven that the group that took Prozac and curcumin fared best. This shows that curcumin is as effective as an antidepressant. Curcumin boosts brain-derived neurotrophic factor levels, potentially reversing some of these changes.
Source : Healthline.com