Italy's Sinner, the world number one, had won his last five encounters against Medvedev - including January's Australian Open final.

But Russian fifth seed Medvedev avenged that Melbourne result with a 6-7 (7-9) 6-4 7-6 (7-4) 2-6 6-3 win after more than four hours on Centre Court. "I knew if I wanted to beat Jannik then I knew it was going to be a tough match," said Medvedev, who is targeting a first appearance in the SW19 final.

"I'm really happy to win, really happy with my game and looking forward."

The 28-year-old will face defending champion Carlos Alcaraz or Queen's Club winner Tommy Paul in the semi-finals.

(Agencies)